A top commander from the Iranian-backed Palestinian militant group Islamic Jihad was killed in a rarely targeted strike in the Gaza Strip on Tuesday, while militants responded by firing rockets at Israeli cities, including Tel Aviv.

In the most serious escalation in months, an Israeli missile attack also targeted the home of an Islamic Jihad official in Damascus, killing two people including one of his sons, Syrian state media said.

Islamic Jihad said the target was the home of political leader Akram Al-Ajouri.

Hours later, sirens sounded in central Israeli cities, including the commercial capital of Tel Aviv the military and witnesses said, warning of possible rocket launches from the Gaza Strip.